RAMP2 anticorps

N° du produit ABIN2730448

Cet anticorps Souris Monoclonal détecte spécifiquement RAMP2 dans WB, IHC et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour RAMP2 anticorps (ABIN2730448)

Antigène: RAMP2 (Receptor (G Protein-Coupled) Activity Modifying Protein 2 (RAMP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RAMP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 4E5

Détail du produit anti-RAMP2 anticorps

Attributs du produit: Homo sapiens receptor (G protein-coupled) activity modifying protein 2 (RAMP2)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinat protein of human RAMP2(NP_005845) produced in HEK293T cell.

Isotype: IgG1

Information d'application

Indications d'application: WB 1:1000, IHC 1:150, FLOW 1:100,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur RAMP2

Antigène: RAMP2 (Receptor (G Protein-Coupled) Activity Modifying Protein 2 (RAMP2))

Autre désignation: RAMP2

Sujet: The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.

Poids moléculaire: 15.8 kDa

ID gène: 10266

NCBI Accession: NM_005854

HGNC: 10266

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling